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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious illnesses, allowing healthcare professionals to choose the appropriate test the first time. Patients benefit from quicker diagnosis and a more specific treatment. Clinicians benefit from a better stewardship of antibiotics. Labs improve efficiency and cost savings. The BioFire FilmArray Pneumonia plus panel (PN panel) examines native sputum, endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 pathogens that are clinically relevant and antimicrobial resistance genes, with semiquantitative results that take less than an hour. Respiratory The burning of biomass (wood plants, trees and other organic material) produces gaseous pollutants and fine particulate matter which negatively impact the respiratory system. Moreover, the environmental problems caused by forest fires such as droughts, can be potentiated by climate change, which can increase their negative impact on human health. In the United States, wildfire smoke has been associated with hospitalizations for respiratory diseases like asthma, COPD and lung cancer. In addition, this type of air pollution is a risk factor for cardiovascular diseases and a major contributing factor to the burden of disease for the most vulnerable population which includes those who are of lower socioeconomic status (SES). During the COVID-19 epidemic, many communities were exposed to harmful levels of air pollution due to wildfires. However, the public health response to this environmental issue has been sporadic and mostly focused on communicating about the management of symptoms. This knowledge gap is alarming, given the evidence that smoking cigarettes and other sources of air pollution can cause health problems. Researchers are currently evaluating the best ways to protect public health during future events of this kind. NIH funds research on this crucial public health issue through the BLUE CORAL and FIRE CORAL studies. For the first time, a prospective study will examine the long-term effects of exposure to smoke from wildfires or other sources. FIRE CORAL enrolls adults who are admitted to hospital for COVID-19 index episodes and speak English or Spanish however, they are not pregnant. The protocol for FIRE CORAL includes a battery of tests conducted in-person, objectively measuring lung function tests and pulmonary imaging, as well as functional assessment. The lungs are especially sensitive to the effects of smoke and other particles due to the fact that they can trigger or worsen chronic respiratory diseases, such as emphysema and COPD and increase the risk of contracting pneumonia. Smoke exposure can cause adverse consequences for health. To minimize or avoid these negative effects, avoid outdoor activities and use the EPA “N95” mask. The mask is designed to catch small particles. Smoking can also cause irritation to the eyes, throat and nose. To help reduce symptoms, drink plenty of water and take medication to reduce inflammation, like corticosteroids. Bloodstream The bloodstream is your first line of defense against germs that invade your system. Special cells called dendritic cells are like the fire department's call center. they take antigens (molecules that trigger an immune response) from invading germs and release proteins to trigger other white blood cells to come to fight them. The total white blood cells, differentials, and band cells increased after firefighters' firefighting tasks, compared to levels after vigorous exercise that did not include firefighting. Skin Dermatologists were concerned about the smoke and ash that resulted from the California wildfires could cause negative effects on the skin of those exposed to these substances. Maria Wei is a graduate student from University of California, Irvine. She investigates how the extreme pollution from wildfires affects the skin. Her research was published on April 22 2012 in Scientific Reports. The research of Wei shows that the temperature of the skin changes depending on the length of time that the body is exposed to flames. It takes upwards of two hours for a person's skin to reach its flash point—the temperature at which it starts to burn and then turns ashy. It's important not to stay close to a fire or campfire and wear protective clothing if going outside on a hot or humid day. While it's important to take precautions against fire-related pollution, there's no way to stop forest fires from occurring. Wei predicts that as climate change causes forests to burn more quickly, the number of people suffering from wildfires will grow. This means that more people will need to wear hats and long sleeves as well as thick moisturizers. It's also worth noting that atopic dermatitis (itchy skin) that a lot of people suffer from can be exacerbated by air pollution from wildfires. It is believed that this is because the particles in smoke can clog pores, thereby making the condition worse. Atopic dermatitis can cause people to be more sensitive to UV light. This can be made worse by smoke from wildfires. This can cause people to be more likely to seek out tanning salons and could cause them to tan with less protection than they should. While a fire and ice facial may reduce the effects of atopic skin dermatitis, it is not safe for those with an open wound or a rash on their face. This treatment is not recommended for patients who have active acne, or if you're pregnant or nursing. The IS Clinical Fire & Ice Facial, at Novuskin Las Vegas' premier membership MedSpa is a results-driven, intensive facial that bridges the mild facelift and the peel, with no time off. It's designed to smooth skin, improve rosacea, reduce fine lines and acne scarring, as well as stimulate cellular renewal. It's an amazing treatment to give yourself radiant skin. Infections The human body is a multi-faceted network of organs and tissues that work together to protect us from infection. Infections can be caused by microorganisms such as bacteria, viruses and parasites which infect healthy cells, causing them to multiply uncontrollably. Your immune system can react by displaying signs of illness. These symptoms can be anything from a snoring nose to a stomach that is upset, but can also include a fever, swollen lymph glands or an itchy skin rash. The type of infection and its location can impact the symptoms. Infections can spread in a variety of ways but the most prevalent are transmitted from person to person via droplets that remain in the air after sneezing or coughing. This is how bacterial infections such as tuberculosis, strep and meningococcal disease as well as viral infections, such as the common cold and influenza are transmitted. Certain bacterial infections like skin infections or sexually transmitted diseases (STIs) such as Chlamydia and gonorrhea can be transmitted by direct contact with infected mucous or tissue surfaces, or indirectly through contaminated surfaces. Certain bacterial infections are transmitted by insects such as mosquitoes, ticks or fleas, and are spread by bites from these bugs you. Infections, parasites, and other microorganisms are small enough to be able to get into the bloodstream and cause infection to your cells. bio-ethanol fireplaces can lead to serious diseases such as the common cold or AIDS. Fungi are responsible for a myriad of skin conditions such as ringworm, athlete's foot. Other types are a threat to the lungs and nervous system, such as the rabies virus. The BioFire PN Panel employs our unique FilmArray technology to analyze a complete list of pathogens that are involved in upper respiratory infections in sputum or the bronchoalveolar lavage samples. The kit includes an reagent pouch that houses all the chemistry needed to perform reverse transcription PCR, nested multiplex analysis and detection on a single machine. This is a straightforward solution that aids clinicians in identifying and treat patients who have a variety respiratory symptoms. This test has been given an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high complexity laboratories.